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Cardiac Markers – BNP

Rapid measurement of BNP to determine if a patient presenting with shortness of breath may be suffering from congestive heart failure.

BNP is secreted by cardiomyocytes and can inhibit the proliferation of vascular smooth muscle cells and fibroblasts, playing an important role in vascular remodeling and blood pressure regulation. In case of hypervolemia or other conditions causing ventricular stretch, the body synthesizes BNP and secretes it into the blood to control the balance of body fluid and electrolyte through interaction with renin angiotensin aldosterone system (RAAS). In cardiovascular diseases such as congestive heart failure, hypertension, acute myocardial infarction, myocardial hypertrophy and cardiomyopathy, B-type brain natriuretic peptide gene expression, synthesis and secretion are significantly increased. Therefore, brain natriuretic peptide can be used in the auxiliary diagnosis of heart failure.

Product Detail

Product Tags


24 strips/box、48 strips/box

Major Components

Microparticles(M): 0.13mg/ml Microparticles coupled with anti brain natriuretic peptide antibody
Reagent 1(R1): 0.1M Tris buffer
Reagent 2(R2): 0.5μg/ml Alkaline phosphatase labeled anti brain natriuretic peptide antibody
Cleaning solution: 0.05% surfactant、0.9% Sodium chloride buffer
Substrate: AMPPD in AMP buffer
Calibrator(optional): Brain natriuretic peptide antigen
Control materials(optional): Brain natriuretic peptide antigen


1.Components are not interchangeable between batches of reagent strips;
2.See the calibrator bottle label for calibrator concentration;
3.See the control bottle label for the concentration range of controls;

Storage And Validity

1.Storage: 2℃~8℃, avoid direct sunlight.
2.Validity: unopened products are valid for 12 months under specified conditions.
3.Calibrators and controls after dissolved can be stored for 14 days in 2℃~8℃ dark environment.

Applicable Instrumen

Automated CLIA System of Illumaxbio (lumiflx16、lumiflx16s、lumilite8、lumilite8s).

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